How tamoxifen works

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  1. s_zagrivyi XenForo Moderator

    How tamoxifen works


    While estrogen is often a hormone more associated with women, there are several reasons why tamoxifen, a drug used to block the effects of estrogen, may be used to treat men. Men who get breast cancer are often treated with a course of tamoxifen. It can also be useful to stop or reverse a condition called gynecomastia, where the breast tissue of adolescent boys or men grows and sometimes becomes uncomfortable. Another use is tamoxifen for men who take anabolic steroids, in order to block the large amounts of estrogen produced by their bodies once they stop taking them. One of the primary uses of tamoxifen for men is the treatment of breast cancer. While this type of cancer is fairly rare in men, the type that most men get involves tumors that are estrogen receptor-positive, meaning that estrogen encourages their growth. Since tamoxifen is a selective estrogen receptor modulator, or SERM, it helps to keep estrogen from binding to the proteins on these tumors and therefore inhibits their growth. There are also some less common but more serious side-effects - tell your doctor about any unusual vaginal bleeding, any pains in your leg or breathlessness, and any allergic-type reactions. The most common unwanted side-effects are hot flushes, and vaginal discharge and itchiness. Treatment options for breast cancer include surgery, chemotherapy, radiotherapy and hormone treatment. Often a combination of two or more of these treatments is used. Some breast cancers need the female hormone oestrogen to grow. The cells of these cancers have receptors on their surface that oestrogen can attach to and are called 'hormone receptor-positive' cancers. Tamoxifen works by blocking the receptors and this prevents oestrogen from reaching cancer cells, stopping them from growing. Some medicines are not suitable for people with certain conditions, and sometimes a medicine may only be used if extra care is taken.

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    Figure 5.9 below shows how tamoxifen works. Hormone receptor-positive breast cancers need estrogen and/or progesterone female hormones produced in the. Tamoxifen is a hormone therapy drug used to treat ER+ breast cancer in pre- and post-menopausal women. Learn about how tamoxifen works and its side. Tamoxifen belongs to a class of drugs called selective estrogen receptor modulators SERMs, and it works by binding the estrogen receptor to body tissue, which in turn affects how much estrogen is.

    You’ve finished treatment for breast cancer and your oncologist has said you are cancer-free “as far as we know.” But one tussle with the Big C is enough; you don’t want a recurrence. Or maybe you have a high risk of getting breast cancer. Perhaps you have a strong family history, genetic predisposition and/or have had some concerning biopsies. You don’t want to have to face cancer; you’d rather try to prevent it in the first place. Either way, you’re a good candidate — if you’re premenopausal — for tamoxifen. A powerful chemotherapy treatment that’s been used for more than 30 years, tamoxifen decreases the chances of breast cancer occurrence or recurrence by about 50%, according to Worta Mc Caskill-Stevens, MD, MS, medical oncologist and Chief of the Community Oncology and Prevention Trials Research Group at the National Cancer Institute. That benefit doesn’t disappear the minute you pop your last pill, either. It works by binding to estrogen receptors and blocking the effects of estrogen (a natural female hormone) in the breast tissue. This slows down the growth and multiplication of breast cancer cells. Tamoxifen is a medicine, which works against estrogen, a female sex hormone. It is used in the treatment of estrogen dependent breast cancer in women. It may also be used in the treatment of estrogen-dependent breast cancer in males. The number of doses you take each day and the duration depends on your medical problem. Take your tablet at about the same time every day to ensure consistent levels of medicine in your body. Treatment with Tamoxifen may be long term and you may require to take it for several years. If you forget to take a dose of Tamoxifen, take it as soon as you remember.

    How tamoxifen works

    How tamoxifen works, Tamoxifen Breast Cancer Care

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  7. Tamoxifen is an "anti-estrogen" and works by competing with estrogen to bind to estrogen receptors in breast cancer cells. Tamoxifen is formally known as a.

    • Basic Information On Tamoxifen Breast Cancer Treatment..
    • How Tamoxifen Works - MedShadow.
    • How does Tamoxifen work?.

    How tamoxifen works. Tamoxifen is an a hormone-based medication. It works by binding to oestrogen receptors and blocks the effects of oestrogen a natural female hormone in the breast tissue. Medical professionals often recommend tamoxifen for men who have breast cancer or gynecomastia. Some men also use it off label to. Tamoxifen, sold under the brand name Nolvadex among others, is a medication that is used to prevent breast cancer in women and treat breast cancer in women and men.

     
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