Prednisone history

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  1. ilyfedotov Well-Known Member

    Prednisone history


    Prednisone is a drug that belongs to the class of corticosteroids which is a steroid. Steroids are hormones with similar chemical structure that gather together as a group. In general, Prednisone is produced by your adrenal gland which is located on top of kidneys. It is used to treat people who have low levels of corticosteroids. It works in preventing the flammable substances in the body. Patients with the following conditions can be treated with Prednisone: skin conditions, lupus, arthritis, breathing disorder, or allergic disorder at regular doses, or it can be treated with cancer at higher doses. This drug is no t highly recommended since it has really severe side effects. Prednisone is a medication designed to prevent the release of substances in the body that can cause inflammation, thereby lowering redness and swelling. It can treat low corticosteroid levels, or other conditions in patients with normal corticosteroid levels, such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, and breathing disorders. Prednisone can also be used to treat the symptoms of certain types of cancer. It is sometimes used with antibiotics to treat a certain type of pneumonia in patients with HIV/AIDS. Prednisone is available as a tablet, a liquid, and a concentrated solution, designed to be taken orally. Dosing and schedule depends entirely on the patient and the condition being treated. The NIH recommends discussing any grapefruit and grapefruit juice intake with your doctor, as it can affect the absorption of the medication.

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    Arthur Nobile was the one who identified the structure of Prednisone in 1950. Not until 1955, Prednisone synthesis was. Historyedit. The first isolation and structure identifications of prednisone and prednisolone were done in 1950 by Arthur Nobile. The first. Dec 12, 2018. Regardless of mental health history, if a doctor wants to prescribe prednisone, it may help to have an understanding of how it may affect mood.

    Prednisone is used for many different autoimmune diseases and inflammatory conditions, including: asthma, COPD, CIDP, rheumatic disorders, allergic disorders, ulcerative colitis and Crohn's disease, adrenocortical insufficiency, hypercalcemia due to cancer, thyroiditis, laryngitis, severe tuberculosis, urticaria (hives), lipid pneumonitis, pericarditis, multiple sclerosis, nephrotic syndrome, sarcoidosis, to relieve the effects of shingles, lupus, myasthenia gravis, poison oak exposure, Ménière's disease, autoimmune hepatitis, giant-cell arteritis, the Herxheimer reaction that is common during the treatment of syphilis, Duchenne muscular dystrophy, uveitis, and as part of a drug regimen to prevent rejection after organ transplant. It is important in the treatment of acute lymphoblastic leukemia, non-Hodgkin lymphomas, Hodgkin's lymphoma, multiple myeloma, and other hormone-sensitive tumors, in combination with other anticancer drugs. Prednisone can be used in the treatment of decompensated heart failure to increase renal responsiveness to diuretics, especially in heart failure patients with refractory diuretic resistance with large dose of loop diuretics. In terms of the mechanism of action for this purpose: prednisone, a glucocorticoid, can improve renal responsiveness to atrial natriuretic peptide by increasing the density of natriuretic peptide receptor type A in the renal inner medullary collecting duct, inducing a potent diuresis. Short-term side effects, as with all glucocorticoids, include high blood glucose levels (especially in patients with diabetes mellitus or on other medications that increase blood glucose, such as tacrolimus) and mineralocorticoid effects such as fluid retention. The mineralocorticoid effects of prednisone are minor, which is why it is not used in the management of adrenal insufficiency, unless a more potent mineralocorticoid is administered concomitantly. It can also cause depression or depressive symptoms and anxiety in some individuals. This means your healthcare provider has given it to you as part of a treatment plan. Prednisone is part of a group of drugs called corticosteroids (often called "steroids"). Other steroid drugs include prednisolone, hydrocortisone, and methylprednisolone. Prednisone can be given in different ways, including pill, injection, and inhaled. It is usually given as a pill when used after a kidney transplant, or for certain kidney disorders. Steroid drugs, such as prednisone, work by lowering the activity of the immune system. Steroids work by slowing your body’s response to disease or injury. Prednisone can help lower certain immune-related symptoms, including inflammation and swelling.

    Prednisone history

    Prednisone Uses, Dosage, Side Effects, Warnings -, Prednisone - Wikipedia

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  6. Nov 19, 2013. Prednisone is a medication designed to prevent the release of substances in the body that can cause inflammation, thereby lowering redness.

    • What is Prednisone? - Live Science.
    • Could Prednisone Cause Mood Swings? - Verywell Health.
    • Prednisone Oral - WebMD.

    Prednisone is metabolised to prednisolone and exerts predominantly glucocorticoid. Congestive heart failure; diabetes mellitus including a family history of;. If you have a history of allergies to prednisone or other steroid drugs; Other medications you are currently taking; If you have diabetes; Whether you have high. A history of significant steroid discoveries and developments originating at the. include the discovery of the antiinflammatory corticosteroid drugs prednisone.

     
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