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    I've been on Tamoxifen since about November last year, I'm very lucky in that I am no longer receiving any other treatments now but recently I have had terrible mood swings, for around the last month or so I can go from sad, to irritated by the tiniest thing, to really rageful within minutes, crying for no reason seems to be my lastest thing. But I'm sure it's just another thing to put up with... All very frustrating as I don't want to feel this way, have lots to look forward to and am lucky to have lovely friends and family so am struggling with my recent moods and hoping that tamoxifen may be the culprit and I'm not just slowly going mad ! Ness x Hi Ness, Sad to hear you too are suffering ( reassuring to know I'm not alone though) I know the night sweats are ridiculous sometimes, not looking forward to winter and central heating, sure there will be a thermostat battle between me and my partner and me opening a sneaky window. day to day is startingto become a struggle, has anyone else had this experience ??? Aside from the night sweats which are horrible and the hot flushes mood swings are something I'm really suffering with. I feel terrible because it's my kids that get the brunt of it. Will let you know if I get any info/reassurance from my Dr next time I see them(Your little one is v cute Hi Chelle and Ness, I do smypathise with both of you. I had two years on hormone therapy for prostate cancer and am with what you say about hot flushes and night sweats. I ended up having a competition with my wife to see who could have the most and I was way out in front both for the amount and also the severity. Allthough I suffered from mood swings, I never did get angry but I did used to find when I heard somthing sad or even somthing good, I often used to have tears running down my face which as a man I found very hard as I had no control over it. One night I thought my wife was in the kichen and there was some thing on the tele about this animal of a father who helped by his wife had tried to rape his 18 month old daughter. The tears just ran down my face when suddenly my wife who had come in the room behind me said "Are yoiu crying"? Can Tamoxifen cause Anxiety Attacks? - Treato Antidepressants That Interact With Tamoxifen - Verywell Health Side Effects to Expect on Tamoxifen Breast Cancer Nalie
     
  5. MiF Well-Known Member

    Tamoxifen for Low Testosterone in Males My previous article discussed the use of clomiphene for increasing testosterone in hypo-gonadal males. Clomiphene works as an estrogen receptor blocker in the hypothalamus, thus stimulating LH/FSH which then stimulate testicular testosterone production. Tamoxifen Another drug which similarly blocks estrogen receptors is Tamoxifen (tamoxiphen), commonly used in breast cancer survivors to block estrogen receptors. Similar to the use of clomiphene, tamoxiphen has been used to treat low testosterone and low sperm counts (infertility) in males. (1-3) Usual dosage is 10-20 mg tamoxifen per day for 6 to 9 months.(1-3) Reduction of Growth Hormone Levels by Tamoxifen An unwanted effect of tamoxifen is 25% reduction in IGF-1 (growth hormone) levels.(5) Tamoxifen reduced peak Growth Hormone levels in mice by 60%.(6) Ocular Toxicity Adverse effects of tamoxifen relate to the ocular toxicity. Regular eye exams at the ophthalmology office every 6 months is advised (4) Articles with related interest: pubmed/640052 Fertil Steril. Hormonal effects of an antiestrogen, tamoxifen, in normal and oligospermic men. The administration of tamoxifen, 20 mg/day for 10 days, to normal males produced a moderate increase in luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone, and estradiol levels, comparable to the effect of 150 mg of clomiphene citrate (Clomid). However, whereas Clomid produced a decrease in the LH response to LH-releasing hormone (LHRH), no such effect was seen after the administration of tamoxifen. Tamoxifen to treat male pubertal gynaecomastia - ScienceDirect The ULTIMATE Clenbuterol Cycle for Amazing Tamoxifen for Low Testosterone in Males - Jeffrey Dach MD
     
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