Tamoxifen (Nolvadex) has been used for over 40 years to treat hormone-receptor positive early, locally advanced and metastatic breast cancers. Learn about tamoxifen and other hormone therapies for metastatic breast cancer. Hormone receptor-positive breast cancers need estrogen and/or progesterone (female hormones produced in the body) to grow. Tamoxifen attaches to the hormone receptor in the cancer cell, blocking estrogen from attaching to the receptor. This slows or stops the growth of the tumor by preventing the cancer cells from getting the hormones they need to grow. Tamoxifen is a pill taken every day for 5-10 years. For premenopausal women, tamoxifen may be combined with ovarian suppression. The benefits from tamoxifen last long after you stop taking it. Tamoxifen (Nolvadex®) is a medication in pill form that has been used for more than 25 years to treat breast cancer in women and men. Tamoxifen is one of the most common endocrine therapy drugs. It has been shown to decrease the chance of recurrence in some early-stage breast cancers and to prevent the development of cancer in the opposite breast. Tamoxifen can also slow or stop the growth of cancer cells present in the body. There are an estimated 29 million women at increased risk for breast cancer in this country, and tamoxifen may offer another alternative to watchful waiting or prophylactic (preventative) mastectomy. Tamoxifen is classified as a selective estrogen receptor modulator (SERM) and works as an anti-estrogen: While the hormone estrogen promotes the growth of breast cancer cells, tamoxifen works by blocking estrogen from attaching to estrogen receptors on these cells. By blocking the estrogen receptors, it is believed that the growth of the breast cancer cells will be halted. Viagra australia next day delivery Buy cheap prednisone I have taken Tamoxifen for about three and a half years with only a few side effects. I do get stiff joints but I don't know whether to blame the. I have also been advised that as I am pre-menopausal, I will be prescribed Tamoxifen for the next ten years. This is a daunting prospect for me. Breast Cancer Discussion Forums - Access the shared knowledge of. I started Tamoxifen on Oct 2016 and the side effects are really effecting. TJL3 wrote: hello- this is my first post- please be patient :)I started Tamoxifen on Oct 2016 and the side effects are really effecting my quality of life. Has anyone found a way to deal with the side effects ( dry eyes, leg cramps, weight gain, vaginal dryness, and just moody). Any advice is welcomex Log in to post a reply Feb 2, 2017 AM Moderators wrote: Hi TJL3, Welcome to the BCO discussion baords! We glad that you found us here and hope that the baords will be a good source of support and information for you. Many many members will understand your experience on Tamoxifen. You will find lots of other members to talk with in the very active thread in the link below. Bottle o Tamoxifen Wishing you well, The Moderators. Feb 2, 2017 PM Lovinggrouches wrote: I've had the same problems. I use refresh vaginal gel once weekly to help out I have gained 15 pounds, have some mental fog issues and insomnia for which I take a prescription med. "We found that for women at the lower end of the high-risk range for developing breast cancer, there is a very small likelihood that taking tamoxifen will reduce mortality," said Joy Melnikow, professor of family and community medicine at UC Davis School of Medicine and Medical Center. "This would support revising the current recommended risk threshold for physicians to counsel women about tamoxifen." Tamoxifen was approved by the U. Food and Drug Administration in 1998 for breast cancer prevention in women who have at least a 1.67-percent chance of developing the disease over the next five years. Preventive Services Task Force and the Canadian Task Force on Preventive Health Care recommend that physicians counsel women above this threshold about the benefits and risks of tamoxifen as a means of preventing the disease. Such women are considered at high risk for breast cancer. Tamoxifen is a selective estrogen receptor-modulating drug used to treat estrogen receptor-positive breast cancers. In addition, it has been shown to reduce the incidence of invasive breast cancer among high-risk women by up to 49 percent. However, tamoxifen is associated with significant adverse effects, including cataracts requiring surgery, deep vein thromboses, endometrial cancer and stroke. Women taking tamoxifen, if they do develop breast cancer, are also more likely to develop an estrogen receptor-negative tumor, which has a worse prognosis. In the new study, Melnikow and her colleagues calculate that tamoxifen can be expected to extend life expectancy only when a woman's five-year risk of developing breast cancer reaches 3 percent or more. Tamoxifen forum Tamoxifen for Breast Cancer Treatment - Side Effects Susan G., Tamoxifen advice Cancer Chat Cialis users forumNolvadex depressionCialis tadalafil buy onlineAmoxicillin sinusitisAzithromycin 1 gm single dose Nov. 2012. Startseite · Forum. Eine Bekannte von mir, die 5 Jahre Tamoxifen eingenommen hat, hat mir. Ich nehme seit fast zwei Jahren Tamoxifen. Tamoxifen und die Nebenwirkungen - BRIGITTE Community. Breast Cancer Topic Discouraged on Tamoxifen. Tamoxifen Viele Frauen brechen Therapie ab Pharmazeutische.. Find information about tamoxifen, a medicine to treat breast cancer, from Cleveland Clinic, including side effects, precautions, concerns, and more. Hallo, ich weiß dass hier schon viel über Tamoxifen und die NW geschrieben wurde. Ich nehme seit ca. einem Jahr Tamoxifen, Am Anfang. Auch er besetzt die Östrogenrezeptoren der Krebszelle, schalten sie aber vollständig aus, während bei Tamoxifen eine Restaktivität bestehen bleibt. Zudem.